CHIRAL PHOSPHINE LIGANDS FOR ASYMMETRIC HYDROGENATION

The monograph provides the reader with a broad view of the challenges and opportunities related to the use of phosphine ligands in stereoselective catalytic hydrogenation. The structure of the title compounds offers a range of possibilities related to the choice of the type of chirality, as well as their modification and substitution. This is to develop a unique structure that works with maximum asymmetric induction under certain conditions. The selection of these conditions is an optimization process running in parallel with the development of the ligand structure. The results of such studies are in many cases striking in terms of scientific quality, and the result of a series of iterative processes is the development of processes leading to practically enantiomerically pure products, often bioactive.

• Broad view of the use of phosphine ligands.
• Range of possibilities related to the choice of chirality type.
• Unique structure working with maximum asymmetric induction.
• Optimization process parallel to ligand structure development.
• Striking results in terms of scientific quality.
• Processes leading to enantiomerically pure products.
• Bioactive products as a result of research.

This monograph is the result of many years of work by Elżbieta Łastawiecka, an experienced researcher in the field of organic chemistry and asymmetric catalysis. Her passion and commitment to research on phosphine ligands contributed to the creation of this comprehensive study. This book is an excellent source of knowledge for students, doctoral students and scientists dealing with organic chemistry, catalysis and asymmetric synthesis.

UMCS, the publisher of this monograph, is a renowned university that has been supporting the development of science and research in Poland for years. The UMCS Publishing House ensures the high quality of published materials, offering readers access to the latest scientific achievements. Thanks to careful editing and correction, this monograph meets the highest editorial standards.

The format of the book (250x176x6 mm) makes it comfortable to read and easy to store. The paperback binding ensures durability and an aesthetic appearance. This monograph is not only a valuable source of knowledge, but also an elegant addition to the library of every chemist.

The year of publication (2020) guarantees that the monograph contains current information and reflects the latest trends in research on phosphine ligands. The number of pages (97) shows that the material is presented in a concise and focused manner, which facilitates learning.